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Figure 1: Bacillary Subpopulations in Active Tuberculosis - Mitchison’s Hypothesis. Circles represent the subpopulations of M. tuberculosis that vary in metabolic activity and multiplication; size of the circles is not proportional to the actual size of the subpopulation. Drugs active against the respective subpopulation appear in italics. INH = isoniazid; PZA = pyrazinamide; RMP = rifampicin; SM = streptomycin[14]

Figure 1: Bacillary Subpopulations in Active Tuberculosis - Mitchison’s Hypothesis. Circles represent the subpopulations of M. tuberculosis that vary in metabolic activity and multiplication; size of the circles is not proportional to the actual size of the subpopulation. Drugs active against the respective subpopulation appear in italics. INH = isoniazid; PZA = pyrazinamide; RMP = rifampicin; SM = streptomycin[14]