Year : 2009 | Volume
: 25 | Issue : 2 | Page : 195--198
Evaluating graft function in pediatric recipients for living donor renal transplantation: Is laparoscopic donor nephrectomy safe?
Shashikant Mishra, Arvind Ganpule, V Muthu, Ravindra B Sabnis, Mahesh R Desai
Department of Urology and Nephrology, Muljibhai Patel Society for Research in Nephrourology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India
Objective: To evaluate the surgical and functional outcomes of laparoscopic graft procurement in pediatric patients undergoing renal transplantation.
Materials and Methods: A retrospective chart review of the cohort records of 54 pediatric living donor renal transplant recipients from 1985 through June 2006 was performed. We compared results of laparoscopic donor nephrectomy (LDN, n = 15) and open donor nephrectomy (ODN, n = 39). Parameters analysed included donor technique and morbidity, operative complications, immediate postoperative renal function, the incidence of early and delayed graft function, and long-term graft survival.
Results: The mean age of these recipients was 14.8 years (5-18) in the LDN group and 13.9 years (8-18) in ODN group. Serum creatinine (mg/dl) was 1.5 ± 0.7 vs 1.8 ± 1.3 at day 1 (P = 0.20), 1.0 ± 0.3 vs 1.4 ± 1.3 at day 2 (P = 0.12), 1.1 ± 0.9 vs 1.3 ± 1.0 at day 7 (P = 0.25), 1.2 ± 0.5 vs 1.6 ± 1.8 (P = 0.20) at day 14, 1.1 ± 0.7 vs 1.2 ± 1.4 (P = 0.39) at 1 month in LDN vs ODN groups, respectively. Early graft function was 35.7 vs 46.4% in the respective groups. There were two delayed graft function and one graft nonfunction in ODN group. Over all graft and patient survival at 1 year was 86.67 and 82.22% (P = 0.34) in LDN and ODN groups, respectively.
Conclusion: Pediatric recipients of the LDN grafts have outcomes comparable to those of ODN graft recipients. Laparoscopic donor nephrectomy is safe and efficacious for graft procurement for pediatric recipients.
Mahesh R Desai
Department of Urology, Muljibhai Patel Urological Hospital, Nadiad-387 001, Gujarat
|How to cite this article:|
Mishra S, Ganpule A, Muthu V, Sabnis RB, Desai MR. Evaluating graft function in pediatric recipients for living donor renal transplantation: Is laparoscopic donor nephrectomy safe?.Indian J Urol 2009;25:195-198
|How to cite this URL:|
Mishra S, Ganpule A, Muthu V, Sabnis RB, Desai MR. Evaluating graft function in pediatric recipients for living donor renal transplantation: Is laparoscopic donor nephrectomy safe?. Indian J Urol [serial online] 2009 [cited 2021 Apr 12 ];25:195-198
Available from: https://www.indianjurol.com/article.asp?issn=0970-1591;year=2009;volume=25;issue=2;spage=195;epage=198;aulast=Mishra;type=0