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LETTERS TO EDITOR
Year : 2022  |  Volume : 38  |  Issue : 2  |  Page : 159-160
 

Re: Mahajan AD, Mahajan SA. Thulium fiber laser versus holmium:yttrium aluminum garnet laser for stone lithotripsy during mini-percutaneous nephrolithotomy: A prospective randomized trial. Indian J Urol 2022;38:42-7


Department of Urology, AIIMS, Bhubaneshwar, Odisha, India

Date of Submission16-Jan-2022
Date of Acceptance03-Mar-2022
Date of Web Publication1-Apr-2022

Correspondence Address:
Manoj Kumar Das
Department of Urology, AIIMS, Bhubaneshwar, Odisha
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/iju.iju_20_22

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How to cite this article:
Rohith G, Das MK, Mandal S, Nayak P. Re: Mahajan AD, Mahajan SA. Thulium fiber laser versus holmium:yttrium aluminum garnet laser for stone lithotripsy during mini-percutaneous nephrolithotomy: A prospective randomized trial. Indian J Urol 2022;38:42-7. Indian J Urol 2022;38:159-60

How to cite this URL:
Rohith G, Das MK, Mandal S, Nayak P. Re: Mahajan AD, Mahajan SA. Thulium fiber laser versus holmium:yttrium aluminum garnet laser for stone lithotripsy during mini-percutaneous nephrolithotomy: A prospective randomized trial. Indian J Urol 2022;38:42-7. Indian J Urol [serial online] 2022 [cited 2022 May 26];38:159-60. Available from: https://www.indianjurol.com/text.asp?2022/38/2/159/342449


We read the article by Mahajan et al.[1] with utmost interest. We would like to congratulate the authors for the successful publication of their randomized trial on thulium fiber laser (TFL) versus holmium:yttrium aluminum garnet (Ho:YAG) laser for stone lithotripsy during mini-percutaneous nephrolithotomy (mini-pcnl) surgery, which concluded that TFL required less stone disintegrating and operative time compared to Ho:YAG laser.

However, we believe certain aspects require explanation. Stone disintegration time and operative time depend on various stone-related factors such as the stone's size, number, location, and composition. To achieve complete stone clearance, more than one tract might be required to gain access to the renal pelvis, automatically increasing the operative time. In the methodology, it was mentioned that the individual stone volumes were added up in patients with multiple stones. How many patients in each group had multiple stones? Moreover, in how many patients were multiple tracts needed to achieve clearance? Operative time was calculated from initial puncture to exit. We would like to know if the time taken for gaining access (to pelvis) was included as it would affect the operative time?

TFL had proven advantages of lower retropulsion[2] and was believed to be a potential breakthrough in managing ureteric calculi. However, higher heat generation was considered one of the major concerns.[3] We believe that the present study showing higher rates of hematuria (possibly due to excessive heat generation) with TFL might significantly impact the concerns regarding its usage in other realms of stone surgery, especially in ureteric calculi.

The study categorized the type of stone based on the Guy's stone score. Guy's stone score consists of four groups.[4] Authors had stated five groups throughout the manuscript, which will need correction. The proportion of patients with larger stones was higher in the TFL group when compared to the Ho:YAG group (10.6% vs. 50.8%), and the patients in the Ho:YAG group had significantly smaller size calculi than the TFL group (56.1% vs. 25.4%). This difference was statistically significant, which points to the selection bias in the study despite randomization. No allocation concealment was mentioned in the study, which could have minimized the bias. Furthermore, no blinding was performed in the study. No details on sample size calculations were mentioned. Was the trial prospectively registered under the Clinical trials registry of India? If so, the registration can be disclosed in the manuscript. Furthermore, the period and duration of the study were not mentioned in the manuscript.

Overall, the present study, the first randomized trial on TFL versus Ho:YAG laser in mini-pcnl surgery, did show the efficiency of the TFL in improving stone disintegration and operative times.

Financial support and sponsorship: Nil.

Conflicts of interest: There are no conflicts of interest.

 
   References Top

1.
Mahajan AD, Mahajan SA. Thulium fiber laser versus holmium: Yttrium aluminum garnet laser for stone lithotripsy during minipercutaneous nephrolithotomy: A prospective randomized trial. Indian J Urol 2022;38:6.  Back to cited text no. 1
    
2.
Kamal W, Kallidonis P, Koukiou G, Amanatides L, Panagopoulos V, Ntasiotis P, et al. Stone retropulsion with Ho: YAG and Tm: YAG Lasers: A clinical practice-oriented experimental study. J Endourol 2016;30:1145-9.  Back to cited text no. 2
    
3.
Hardy LA, Wilson CR, Irby PB, Fried NM. Thulium fiber laser lithotripsy in an in vitro ureter model. J Biomed Opt 2014;19:128001.  Back to cited text no. 3
    
4.
Thomas K, Smith NC, Hegarty N, Glass JM. The Guy's stone score – Grading the complexity of percutaneous nephrolithotomy procedures. Urology 2011;78:277-81.  Back to cited text no. 4
    




 

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