Rare case of blastemal predominant adult Wilms' tumor with skeletal metastasis case report and brief review of literature

Rashmi Patnayak; D. V. S. Rambabu; Amitabh Jena; Bodagala Vijaylaxmi; BV Phaneendra; M Kumaraswamy Reddy

doi:10.4103/0970-1591.105772

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CASE REPORT

Year : 2012 | Volume : 28 | Issue : 4 | Page : 447-449

Rare case of blastemal predominant adult Wilms' tumor with skeletal metastasis case report and brief review of literature

Rashmi Patnayak¹, D. V. S. Rambabu², Amitabh Jena³, Bodagala Vijaylaxmi⁴, BV Phaneendra¹, M Kumaraswamy Reddy¹
¹ Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
² Department of Urology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
³ Department of Surgical Oncology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
⁴ Department of Radiology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

Correspondence Address:
Rashmi Patnayak
Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh - 517 507
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0970-1591.105772

Wilms' tumor (nephroblastoma) is extremely rare in adults, skeletal metastasis being still rarer. The clinical course of adult Wilms' tumor is very aggressive. The present case is a rare blastemal predominant adult Wilms' tumor presenting with skeletal metastasis. We report a case of 19-year-old female presented with severe low backache and colicky left loin pain of 3 months and progressive weakness of 15 days duration. Magnetic resonance image (MRI) of lumbosacral spine was reported as spinal metastasis with right renal mass. The patient underwent right radical nephrectomy and the tumor was histopathologically confirmed as adult Wilms' tumor. In case of adult Wilms' tumor, distant metastasis may be the first presentation and this possibility should be considered when an adult patient presents with flank pain and a renal mass.

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