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Year : 2010  |  Volume : 26  |  Issue : 1  |  Page : 72-75

Management options for stage 1 nonseminomatous germ cell tumors of the testis

Department of Urology, Indiana University, Indianapolis, Indiana, USA

Correspondence Address:
Stephen D.W Beck
Department of Urology, Indiana Cancer Pavilion, 535 N. Barnhill Drive, Suite 420, Indianapolis, Indiana- 462 02
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-1591.60455

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Management of clinical stage I non seminomatous germ cell tumor includes surveillance, primary chemotherapy and retroperitoneal lymph node dissection. Stratifying clinical stage I disease to high- and low-risk groups for harboring micrometastic retroperitoneal disease (pathologic stage B) is based on pathologic characteristics of the primary tumor. The presence of embryonal dominant histology and lymphovascular invasion (high-risk group) predicts for a 50% incidence of retroperitoneal disease. Low-risk group, the absence of either factor, predicts a 20% chance of retroperitoneal disease. Irrespective of risk classification, all treatment modalities have equal survival rates of 99% to 100%, and differ only in their unique short and long-term modalities. The mode of treatment in clinical stage I disease should remain patient driven and is guided by the perceived morbidities of each therapy.

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