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Year : 2008  |  Volume : 24  |  Issue : 2  |  Page : 273

Ureteroilleal anastomosis in orthotopic ileal neobladders: Does technique matter?

Department of Urology and Renal transplantation, SGPGIMS, Lucknow, UP, India

Correspondence Address:
Aneesh Srivastava
Department of Urology and Renal transplantation, SGPGIMS, Lucknow, UP
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Source of Support: None, Conflict of Interest: None

PMID: 19468416

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How to cite this article:
Gupta P, Muruganandham K, Srivastava A. Ureteroilleal anastomosis in orthotopic ileal neobladders: Does technique matter?. Indian J Urol 2008;24:273

How to cite this URL:
Gupta P, Muruganandham K, Srivastava A. Ureteroilleal anastomosis in orthotopic ileal neobladders: Does technique matter?. Indian J Urol [serial online] 2008 [cited 2022 Dec 2];24:273. Available from:

   Summary Top

In a randomized prospective trial of 60 patients undergoing orthotopic ileal neobladder, Atallah and Mohamed et al . assessed the pros and cons of refluxing and antirefluxing ureteroileal anastomosis. Patients underwent direct anastomosis of ureter on one side and antireflux serous lined extramural tunnel on the contralateral side. [1] Glomerular filtration rate (GFR) wa~ 15 patients. One patient had prolonged leakage from a refluxing uretero-ileal anastomosis, which was managed with temporary percutaneous nephrostomy. Early anastomotic strictures developed in six patients, one with direct and five with antirefluxing technique. Strictures were more common on left than right side (4 vs. 2). Out of these six patients, three were treated with double J-stenting and transurethral endoureterotomy while other three required open ureteric reimplantation. The mean presurgery GFR decreased from 48.6 to 31.8 ml/min after managing these stricture units (P = 0.01).

   Comments Top

This is a well-designed, prospective, randomized study comparing antireflux and direct uretero-ileal anastomosis in the same patient with an orthotopic ileal neobladder.

The orthotopic bladder substitute has evolved into the most ideal form of urinary diversion available today and it may be considered the gold standard. Controversy exists regarding the need to incorporate an antireflux mechanism in patients undergoing an orthotopic form of urinary diversion. Even though there are many reports in the literature addressing this issue, these are all retrospective studies with their own limitations.

In the present study, the incidence of ureteroileal stricture was five times higher with antirefluxing anastomosis compared to direct method. This is consistent with the reported incidence of anastomotic strictures of 7.8-20.4% after antirefluxing procedures vs. 1.4-3.6% after direct methods. [2],[3],[4] No significant difference in GFR was detected between the methods of uretero-ileal implantation during short-term follow-up. Incidence of asymptomatic bacteriuria also declines steadily with time so as such will not make much difference in GFR later on. [5]

Although the incidence of asymptomatic bacteriuria is more common with the refluxing ureteroileal anastamosis, it gradually decreases over time and it does not affect the renal function. Moreover, the stricture rates are found to be more common with the antirefluxing anastamosis. The results from this well-conducted study support refluxing rather than antirefluxing anastamosis in orthotopic neobladder reconstruction. However, studies with longer follow-up may require to support or contradict this finding.

   References Top

1.Shaaban AA, Abdel-Latif M, Mosbah A, Gad H, Eraky I, Ali-El-Dein B, et al . A randomized study comparing an antireflux system with a direct ureteric anastomosis in patients with orthotopic ileal neobladders. BJU Int 2006;97:1057-62.  Back to cited text no. 1  [PUBMED]  [FULLTEXT]
2.Pantuck AJ, Han KR, Perrotti M, Weiss RE, Cummings KB. Ureteroenteric anastomosis in continent urinary diversion: Long-term results and complications of direct versus nonrefluxing techniques. J Urol 2000;163:450-5.  Back to cited text no. 2  [PUBMED]  [FULLTEXT]
3.Gschwend JE, Volkmer BG, Liske P, Kleinschidt K, Hautmann RE. Type of ureteral anastomosis in orthotopic ileal neobladder: Impact on the rate of hydronephrosis and renal function. J Urol 2005;173:132.  Back to cited text no. 3    
4.Roth S, Van Ahlen H, Sejonow A, Oberpenning F, Hertle L. Does the success of ureterointestinal implantation in orthotopic bladder substitution depend more on surgeon level of experience or choice of technique? J Urol 1997;157:56-60.  Back to cited text no. 4    
5.Abdel-Latif M, Mosbah A, El-Bahnasawy MS, El-Sawy E, Shaaban AA. Asymptomatic bacteriuria in men with orthotopic ileal neobladders: Possible relationship to nocturnal enuresis. BJU Int 2005;96:391-6.  Back to cited text no. 5    


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