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Year : 2008  |  Volume : 24  |  Issue : 1  |  Page : 10-15

Prognostic biomarkers of renal cell carcinoma: Recent advances

Department of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan

Correspondence Address:
Hiroshi Kitamura
Department of Urology, Sapporo Medical University School of Medicine, South 1 West 16, Chuo-ku, Sapporo 060-8543
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-1591.38596

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Recent advances in understanding the characteristics of renal cell carcinoma (RCC) have brought to our attention many prognostic markers that affect and predict the survival outcome of patients with the disease. For the moment, however, patients with RCC have not received any benefit from such markers. If a patient is diagnosed as "high risk" by using such prognostic markers, there is no promising systemic therapy available. In this review we mainly focus on biomarkers of RCC that can be applied for therapeutic use reported in recent publications. Several issues and limitations in the reported studies are also highlighted and discussed. Developing biomarkers from the viewpoint of therapeutic application will lead to improvement of the prognosis of RCC patients.

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