| ORIGINAL ARTICLE |
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| Year : 2001 | Volume
: 17
| Issue : 2 | Page : 156-158 |
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A study of the hypo-osmotic swelling test of spermatozoa in both fertile and infertile male subjects and its relationship with the standard spermiogram
Kingshuk Majumdar, Gita Rajagopalan, A Bupathy
Department of Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondichery, India
Correspondence Address:
Kingshuk Majumdar
Plot No. 31, 4th Cross, Thanthai Periyar Nagar Extension, Pondicherry - 605 005
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Objective: To compare the hypo-osmotic swelling test (HOST) of spermatozoa with the standard spermiogram in both fertile and infertile male subjects.
Materials and Methods: The HOST was performed on 50 men of proven fertility and 51 infertile men. The results from both the groups were compared with the standard spermiogram.
Study Design: Prospective case-control study.
Analysis: The statistical analysis was done using the Karl Pearsons coefficient of correlation.
Results: The HOST values were higher in the fertile group. The correlation between hypo-osmotic swelling and semen variables was higher in the infertile group than in the fertile group. 2 patients in the infertile group with greater than 50% hypo-osmotic swelling got their spouses pregnant during the study period.
Conclusion: The HOST is inexpensive, easy to perforrn and can be used to evaluate sperm tail function. It can also be used to predict the fertilizing potential of the semen sample. |
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