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Year : 2001  |  Volume : 17  |  Issue : 2  |  Page : 156-158

A study of the hypo-osmotic swelling test of spermatozoa in both fertile and infertile male subjects and its relationship with the standard spermiogram

Department of Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondichery, India

Correspondence Address:
Kingshuk Majumdar
Plot No. 31, 4th Cross, Thanthai Periyar Nagar Extension, Pondicherry - 605 005
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Source of Support: None, Conflict of Interest: None

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Objective: To compare the hypo-osmotic swelling test (HOST) of spermatozoa with the standard spermiogram in both fertile and infertile male subjects. Materials and Methods: The HOST was performed on 50 men of proven fertility and 51 infertile men. The results from both the groups were compared with the standard spermiogram. Study Design: Prospective case-control study. Analysis: The statistical analysis was done using the Karl Pearsons coefficient of correlation. Results: The HOST values were higher in the fertile group. The correlation between hypo-osmotic swelling and semen variables was higher in the infertile group than in the fertile group. 2 patients in the infertile group with greater than 50% hypo-osmotic swelling got their spouses pregnant during the study period. Conclusion: The HOST is inexpensive, easy to per­forrn and can be used to evaluate sperm tail function. It can also be used to predict the fertilizing potential of the semen sample.

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