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Figure 1: Light microscopy (hematoxylin and eosin staining) of a cross section of the seminiferous tubule (×100) (a) normal seminiferous tubule with spermatogonia near the basement membrane, and spermatocytes, round and elongated spermatid and mature spermatozoa in the lumen after spermiogenesis (release of mature spermatozoa into the lumen). (Johnsen score = 10) (b) normal spermatogenesis as in (a) after zinc supplementation (Johnsen score = 10) (c) scarcity of spermatozoa in the lumen consistent with spermatogenic arrest associated with zinc deficiency (Johnsen score = 6)

Figure 1: Light microscopy (hematoxylin and eosin staining) of a cross section of the seminiferous tubule (×100) (a) normal seminiferous tubule with spermatogonia near the basement membrane, and spermatocytes, round and elongated spermatid and mature spermatozoa in the lumen after spermiogenesis (release of mature spermatozoa into the lumen). (Johnsen score = 10) (b) normal spermatogenesis as in (a) after zinc supplementation (Johnsen score = 10) (c) scarcity of spermatozoa in the lumen consistent with spermatogenic arrest associated with zinc deficiency (Johnsen score = 6)