Indian Journal of Urology
: 2010  |  Volume : 26  |  Issue : 1  |  Page : 76--81

Prognostic features and markers for testicular cancer management

Eddy S Leman, Mark L Gonzalgo 
 Department of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA

Correspondence Address:
Mark L Gonzalgo
Department of Urology, 875 Blake Wilbur Dr - MC 5826, Stanford, CA 94305

Testicular neoplasm accounts for about 1% of all cancers in men. Over the last 40 years, the incidence of testicular cancer has increased in northern European male populations for unknown reasons. When diagnosed at early stage, testicular cancer is usually curable with a high survival rate. In the past three decades, successful multidisciplinary approaches for the management of testicular cancer have significantly increased patient survival rates. Utilization of tumor markers and accurate prognostic classification has also contributed to successful therapy. In this article, we highlight the most commonly used tumor markers and several potential DQnovelDQ markers for testicular cancer as part of the ongoing effort in biomarker research and discovery. In addition, this article also identifies several key prognostic features that have been demonstrated to play a role in predicting relapse. These features include tumor size, rete testis invasion, lymphovascular invasion, and tumor histology. Together with tumor markers, these prognostic factors should be taken into account for risk-adapted management of testicular cancer.

How to cite this article:
Leman ES, Gonzalgo ML. Prognostic features and markers for testicular cancer management.Indian J Urol 2010;26:76-81

How to cite this URL:
Leman ES, Gonzalgo ML. Prognostic features and markers for testicular cancer management. Indian J Urol [serial online] 2010 [cited 2020 Jul 7 ];26:76-81
Available from:;year=2010;volume=26;issue=1;spage=76;epage=81;aulast=Leman;type=0