Indian Journal of Urology
ORIGINAL ARTICLE
Year
: 2007  |  Volume : 23  |  Issue : 1  |  Page : 14--17

Prediction of biochemical failure in localized carcinoma of prostate after radical prostatectomy by neuro-fuzzy


Neeraj Kumar Goyal1, Abhay Kumar1, Rajiba L Acharya1, Udai Shankar Dwivedi1, Sameer Trivedi1, Pratap Bahadur Singh1, TN Singh2 
1 Department of Urology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221 005, India
2 Department of Earth Sciences, Indian Institute of Technology, Mumbai - 4000 76, India

Correspondence Address:
Pratap Bahadur Singh
Department of Urology, Institute of Medical Sciences, Banaras Hindu University Varanasi (UP)
India

Objective: To predict biochemical failure in localized prostate cancer after radical prostatectomy using preoperative variables. Materials and Methods: Twenty-six patients of early carcinoma of prostate underwent open retropubic radical prostatectomy from June 2002 to June 2006. Preoperative variables included age, family history, digital rectal examination, serum prostatic specific antigen (S. PSA), prostate biopsy Gleason score, MRI of pelvis variables like periprostatic extension, seminal vesical invasion, weight of gland and pathological stage. With application of neuro-fuzzy, these variables were fed into system as input and output, that is S. PSA at six months (predicted value) was calculated. Neuro-fuzzy system is a system to combine fuzzy system with learning techniques derived from neural networks. Here, we applied Takagi Sugeno Kang model (TSK) due to its close solution to our aim. All the patients were followed up for a minimum of six months. At six month S. PSA of all patients was done (observed value). Predicted and observed values were compared. Result: Predicted and observed values were plotted on 1:1 slop line. Coefficient of correlation was 0.9935. Conclusion: Coefficient of correlation is close to one. It indicates that the neuro-fuzzy is accurate in predicting biochemical failure in localized carcinoma of prostate after radical prostatectomy.


How to cite this article:
Goyal NK, Kumar A, Acharya RL, Dwivedi US, Trivedi S, Singh PB, Singh T N. Prediction of biochemical failure in localized carcinoma of prostate after radical prostatectomy by neuro-fuzzy.Indian J Urol 2007;23:14-17


How to cite this URL:
Goyal NK, Kumar A, Acharya RL, Dwivedi US, Trivedi S, Singh PB, Singh T N. Prediction of biochemical failure in localized carcinoma of prostate after radical prostatectomy by neuro-fuzzy. Indian J Urol [serial online] 2007 [cited 2020 Jul 5 ];23:14-17
Available from: http://www.indianjurol.com/article.asp?issn=0970-1591;year=2007;volume=23;issue=1;spage=14;epage=17;aulast=Goyal;type=0