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REVIEW ARTICLE
Year : 2015  |  Volume : 31  |  Issue : 4  |  Page : 320-326

Guideline-based management of non-muscle invasive bladder cancer


1 Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN 37232-2765, USA
2 Department of Urologic Surgery, University of Minnesota, Minneapolis VA Healthcare System, Urology Section, Nashville, TN 37232-2765, USA

Correspondence Address:
Justin R Gregg
A-1302 Medical Center North, Vanderbilt University Medical Center, Nashville, TN 37232-2765
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-1591.163305

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Introduction: Non-muscle invasive bladder cancer (NMIBC) represents a broad spectrum of disease, the hallmarks of which include disease recurrence and progression. Clinicians have a number of surgical and therapeutic options at their disposal when treating this disease, and the underlying evidence continues to evolve. A number of professional organizations have invested in the development of clinical practice guidelines to guide patient management. Materials and Methods: We review and summarize four major guidelines, the American Urological Association, the European Association of Urology, the International Consultation on Urological Disease and the National Comprehensive Cancer Network. Results: Guideline panels differed in their composition, methodological approach and structure of recommendations. Despite this, many recommendations were similar between various panels, although differences are present in panel recommendations related to initial diagnosis and treatment, adjuvant therapy and disease surveillance. Conclusions: Guideline recommendations are similar at many decision points that clinicians face when managing NMIBC, although they are far from uniform. While future prospective, well-designed studies will hopefully clarify NMIBC management, urologists ultimately must rely on a combination of evidence-based recommendations, which they should seek to integrate with patients' values and preferences and the individual circumstances to provide the best possible patient care.


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