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CASE REPORT
Year : 2015  |  Volume : 31  |  Issue : 2  |  Page : 136-138

Pseudohyperplastic variant of adenocarcinoma as a component of α-methyl-CoA-racemase (AMACR negative) carcinosarcoma of the prostate


1 Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt, Delhi, India
2 Department of Urology, Army College of Medical Sciences and Base Hospital, Delhi Cantt, Delhi, India

Correspondence Address:
Prof. Col. Ajay Malik
Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-1591.152921

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Carcinosarcoma (CS) or Sarcomatoid carcinoma (SC) of the prostate is a very rare malignant tumor of the prostate having an aggressive clinical course and dismal prognosis. The adenocarcinomatous element is usually of the acinar type and closely admixed with a sarcomatous component. We report a case of α-methyl-CoA-racemase (AMACR)-negative pseudohyperplastic variant of adenocarcinoma in CS. To the best of our knowledge, there have been no published case reports of this variant in CS till date. An accurate diagnosis is essential as this uncommon, aggressive cancer has limited therapeutic options


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