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RESEARCH ARTICLE
Year : 2004  |  Volume : 20  |  Issue : 2  |  Page : 95-100

Causes of lower urinary tract symptoms (LUTS) in adult Indian males


1 KCP Nephro-Urological Center and Research Foundation, Pinnamaneni Polyclinic, India
2 Department of Biochemistry, Siddhartha Medical College, Vijayawada, India

Correspondence Address:
C Nageswara Rao
KCP Nephro-Urological Center and Research Foundation, Pinnamaneni Poly Clinic, Siddhartha Nagar, Vijayawada - 520 010
India
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Source of Support: None, Conflict of Interest: None


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Objectives : Evaluation of causes of lower urinary tract symptoms in adult Indian males. Methods : In this study, 1329 men above the age of 40 years from Krishna District of Andhra Pradesh attending the clinics for lower urinary tract symptoms (LUTS) were subjected to detailed physical examination and were given IPSS questionnaire for evaluating LUTS. Special atten­tion was paid to nocturia, as it behaved differently from other LUTS. Results : Of the 1329 men, 480 had specific diseases (i.e. 36%) responsible for occurrence of LUTS (stricture urethra 43%, prostatic enlargement 40%, neurogenic blad­der 8.8%, miscellaneous 8.2%). About 14% of the total subjects (192/1329) had benign prostatic enlargement. Among the 849 men who had some degree of LUTS, no specific disease was found responsible for these symptoms. Nocturia was the most predominant among the symptoms in both groups of subjects and it had a significant impact on IPSS. If nocturia is eliminated, IPSS gets drastically lowered for each age group irrespective of the presence or absence of disease. Conclusions: The study indicated that lower urinary tract symptoms are not just confined to the prostatic en­largement. There could be contribution of several urological and non-urological factors in the etiopatho­genesis of LUTS. The relevance of nocturia in IPSS re­quires careful reconsideration. Thus patients with LUTS need a well-planned assessment of disease process and a clear cut understanding of the relevant pathophysiology and an orderly approach to diagnosis and therapy.


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