Rajeev Kumar Department of Urology, All India Institute of Medical Sciences, New Delhi - 110 029 India
Source of Support: None, Conflict of Interest: None
Introduction: Molecular biologic techniques form the cornerstone of progress in the field of medicine in the next millennium. These techniques are useful in diagnosis, prognosis, management and follow-up of patients.
Methods: Recent publications in the field of molecular biology and its use in urology were reviewed. The material was then edited to produce this article.
Results: There has been a tremendous interest in this field in the last decade. Over 50 articles in indexed journals and edited text books were found. Literature relating to its use in urology is less common but seems to be increasing in the last few years.
Conclusions: Molecular diagnosis is the identification of presence of disease or susceptibility to disease based on the presence of abnormal genes or their products. Molecular therapy is the development of rational therapeutic strategies aimed at correcting the basic genomic abnormality using molecular biologic techniques. These two applications of molecular biology shall be the focus of advance in urology in the next millennium.