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RESEARCH ARTICLE
Year : 2004  |  Volume : 20  |  Issue : 2  |  Page : 160-163

Management of testicular tumors- SGPGIMS experience


Department of Urology & Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

Correspondence Address:
Aneesh Srivastava
Department of Urology & Renal transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow - 226 014
India
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Source of Support: None, Conflict of Interest: None


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Objectives : To assess the single centre experience of multimodality treatment approaches and overall outcome in testicular tumor patients. Methods : In a retrospective study, records of 70 pa­tients were analysed. Seminoma was present in 21 cases, non seminomatous germ cell tumour (NSGCT) in 48 pa­tients and Leydig cell tumor in 1 patient. The clinical stag­ing in seminoma of the testis were stage I in 6 cases, stage IIA in 4 cases, the stage JIB in 2 cases, stage HC in 2 cases and stage III in 7 cases. In the NSGCT group stage I tumor was present in 3 cases, stage IIA in I case, stage IIB in 4 cases, stage IIC in 4 cases and stage III in 36 cases. Adjuvant radiotherapy to retroperitoneum was given in stage I and IIA of seminoma. Primary retroperitoneal lympho node dissection (RPLND) was done in 4 cases of NSGCT and biopsy of lymph nodes was positive for ma­lignant cells in one case. Cisplatinum based chemotherapy was given in stage IIB, JIC and stage III of seminoma and NSGCT Secondary RPLND was done in 2 cases and ex­cision of postchemotherapy residual masses in 14 cases. Results : The patients of stage I NSGCT tumors had recurrence free mean follow-up of 9 years while 1 case of stage IIA was disease free at 1 year of follow-up. All cases of stage IIA, IIB,IIC seminoma and NSGCT patients were alive and doing well on follow-up. In advanced and meta­static tumors, 75% of seminoma and 60% of NSGCT pa­tients were alive and disease free with mean follow-up period of 5 years and 4 years respectively. Conclusions: Excellent prognosis was seen in early stages of testicular germ cell tumors. Advanced and metastatic seminoma showed good prognosis whereas only 60% of such NSGCT are disease free and alive on long-term follow-up.


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