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Year : 1986  |  Volume : 3  |  Issue : 1  |  Page : 26-29

A study of mast cell distribution in tumors of kidney and urinary bladder.


Department of Anatomy, SMS Medical College, Jaipur, Rajasthan

Correspondence Address:
K S Parihar
Department of Anatomy, SMS Medical College, Jaipur, Rajasthan

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Source of Support: None, Conflict of Interest: None


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The distribution of the mast cells was studied in 34 tumors of kidney and 28 tumors of urinary bladder of various types along with 15 normal organs of each for comparison, to find out the mast cell reaction in these neoplasms. All the tumors of kidney recorded an increase, while all the tumors of urinary bladder recorded a decrease in the mast cell population as compared to normal. The tumor parenchyma of all the malignant tumors in the present study did not appear to contain any mast cells. Mast cells were observed only in the connective tissue present in and around the tumor mass (es) and their population appeared to be dependent on the quantity and functional status of the connective tissue present in and around the tumor, which in turn apperaed to be influenced by the type, duration, stage, growth rate and vascularity of the individual tumors coupled with generalized immune reactions and possible local secretions by the tumor itself.


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